Menthol is an organic compound made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above.


Menthol's ability to chemically trigger the cold-sensitive TRPM8 receptors in the skin is responsible for the well-known cooling sensation it provokes when inhaled, eaten, or applied to the skin. In this sense, it is similar to capsaicin, the chemical responsible for the spiciness of hot chilis (which stimulates heat sensors, also without causing an actual change in temperature). Menthol's analgesic properties are mediated through a selective activation of κ-opioid receptors. Menthol blocks calcium channels and voltage-sensitive sodium channels, reducing neural activity that may stimulate muscles. Some studies show that menthol acts as GABAA receptor positive allosteric modulator andincreases Gabaergic transmission in PAG neurons. Menthol also shares anaesthetic properties similar to propofol, by modulating the same sites of the GABAA receptor. Menthol is widely used in dental care as a topical antibacterial agent, effective against several types of streptococci and lactobacilli.

                                                                  CERTIFICATE OF ANALYSIS

                                                                 Product Name: Menthol Crystal                             

Items                         

Specifications

Results

USP39

BP2015

Identification

Colourless, transparent hexagonal or needlelike crystals.

Conform

Melting point(℃)

41~44℃

About 43℃

41.5-42.5℃

Solubility

1g soluble in 5ml of 90%(v/v) alcohol,forming a clear solution

Conform

Limit of Nonvolatile residue (%)

Not overrun 0.05 under condition of 105℃

0.01

Specific rotation(25℃)

-45°~ -51°

About -50°

-49.68°

Organic volatile impurities

Solvent-Use dimethyl sulfoxide

Meets the requirement

Chromatographic purity

The peak response due to menthol is not less than 97%

≥99.4% .

As Content

≤3ppm

<3ppm

Heavy metals

≤10ppm

< 10ppm

Residue on ignition

≤0.1%

0.03%

Related substances

Examine by gas chromatography

Meets the requirement

Conclusion: Complies with BP2015/USP39

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Packing Detail:

25 Kg Drums

Terms of payment: 

Cash/TT